A National Research Council report that identifies for the U.S. Climate Change Science Program the essential elements of effective global change assessments, including strategic framing, engagement of stakeholders, credible treatment of uncertainties, and a transparent interface between policymakers and scientists. The report reviews lessons learned from past assessments, which are intended to inform policymakers about the scientific underpinnings of critical environmental issues such as climate change, loss of biodiversity, and ozone depletion.